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On Demand

Part 1: Efficacy and Effectiveness of Clozapine in Schizophrenia Related Disorders, Risk to Benefit Considerations and Off-Label Use


Total Credits: 4.5 including 4.5 Category II CEs

Instructors:
Deanna Kelly, PharmD, BCPP |  Robert W. Buchanan, M.D. |  Gopal Vyas, DO
Duration:
4 Hours 36 Minutes
Format:
Audio and Video


Description

Part 1 is a duration of 4 hours and 36 minutes.

Session 1: Efficacy and Effectiveness of Clozapine in Schizophrenia Related Disorders, Risk to Benefit Considerations and Off Label Use : 

This video provides approximately 15-minute didactic overview of the efficacy and effectiveness of clozapine in schizophrenia related disorders as well as the risk to benefit considerations and off label use of clozapine with a focus on making sure the participants learn how to describe the efficacy and effectiveness of clozapine in psychotic disorders, compare the efficacy and effectiveness of clozapine with other antipsychotic medications, analyze the risk to benefit considerations of clozapine use, and how to list the off-label uses for clozapine. This is followed by a discussion on the topic between the presenter, other experts and providers. 

Session 2: Pharmacology, Mechanism of Action of Clozapine, and Treatment Guidelines: 

This video provides approximately 15-minute didactic overview of the pharmacology, mechanism of action of clozapine, and treatment guidelines of clozapine with a focus on making sure the participants learn how to describe the proposed mechanism(s) for clozapine, discuss the pharmacological profile of clozapine, use the treatment guidelines for schizophrenia to assess when to use clozapine. This is followed by a discussion on the topic between the presenter, other experts and providers. 

Session 3: How to Determine if Someone has Treatment-Resistant Schizophrenia  

This video provides approximately 15-minute didactic overview of how to determine if someone has treatment-resistant schizophrenia with a focus on making sure the participants learn how to list the criteria by which a patient is determined to have treatment-resistant schizophrenia, describe other reasons that may impact optimal treatment response, and differentiate between treatment resistant symptoms and inadequate medication trials. This is followed by a discussion on the topic between the presenter, other experts and providers. 

Session 4: Barriers to Clozapine Use and Tips for Implementation of Clozapine Use in Team-Based Settings: 

This video provides approximately 15-minute didactic overview of the barriers to clozapine use and tips for implementation of clozapine with a focus on making sure the participants learn how to list the most common barriers to clozapine use, understand barriers that can be best overcome to improve clozapine use, describe how using a team-based approach can facilitate clozapine use. This is followed by a discussion on the topic between the presenter, other experts and providers. 

Handouts

Learning Objectives

· Describe the efficacy and effectiveness of clozapine in psychotic disorders

· Compare the efficacy and effectiveness of clozapine with other antipsychotic medications

· Analyze the risk to benefit considerations of clozapine use

· List some off-label uses for clozapine